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Drug Name: Elotuzumab [USAN:INN]
Description: A humanized monoclonal antibody that selectively targets glycoproteins expressed on myeloma cells.

NCI: A humanized monoclonal antibody directed against the human CS1 (CD2 subset 1, CRACC, SLAMF7) antigen with potential antineoplastic activity. Elotuzumab binds to the CS1 antigen, which may trigger antibody-dependent cellular cytotoxicity (ADCC) in cells expressing CS1. CS1 is a cell surface glycoprotein belonging to the CD2 subset of the immunoglobulin superfamily (IgSF) and is highly expressed by multiple myeloma cells, but minimally expressed by normal cells. (NCI Thesaurus) 



 
 
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Last updated: Aug 2017
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