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Drug Name: Pretomanid [USAN:INN] View Structure
Description: Nitroimidazopyran derived from 5-nitroimidazoles; a prodrug that requires activation by a bacterial F420-depedent glucose-6-phosphate dehydrogenase (Fgd) and nitroreductase to activate components that then inhibit bacterial mycolic acid and protein synthesis. 

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Last updated: Nov 2018