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Drug Name: Abiraterone [INN:BAN] View Structure
Description: A steroidal inhibitor of cytochrome P450(17alpha)/C17-20 lyase.

NCI: abiraterone acetate. An orally active acetate salt of the steroidal compound abiraterone with antiandrogen activity. Abiraterone inhibits the enzymatic activity of steroid 17alpha-monooxygenase (17alpha-hydrolase/C17,20 lyase complex), a member of the cytochrome p450 family that catalyzes the 17alpha-hydroxylation of steroid intermediates involved in testosterone synthesis. Administration of this agent may suppress testosterone production by both the testes and the adrenals to castrate-range levels. (NCI Thesaurus) 



 
 
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