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Drug Name: CEP 9722
Description: NCI: PARP inhibitor CEP-9722 A small-molecule prodrug of CEP-8983, a novel 4-methoxy-carbazole inhibitor of the nuclear enzymes poly(ADP-ribose) polymerase (PARP) 1 and 2, with potential antineoplastic activity. Upon administration and conversion from CEP-9722, CEP-8983 selectively binds to PARP 1 and 2, preventing repair of damaged DNA via base excision repair (BER) ... /NCI Thesaurus



 
 
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Last updated: Aug 2017
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