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Drug Name: Bleomycin A6 hydrochloride View Structure
Description: Forms conjugate with monoclonal antibody anti-CCT2 which binds to leukemia cells.

NCI: Boanmycin hydrochloride. The hydrochloride salt form of boanmycin (aka bleomycin A6), a component of the antibiotic bleomycin produced by Streptomyces species, with potential antineoplastic activity. Upon administration, boanmycin forms complexes with iron that reduce molecular oxygen to superoxide and hydroxyl radicals. This causes single- and double-stranded DNA breaks which eventually leads to cell death. Compared to bleomycin, boanmycin appears to have a more favorable toxicity profile. (NCI Thesaurus) 

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Last updated: Apr 2019