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Drug Name: Indoximod [USAN:INN] View Structure
Description: NCI: A methylated tryptophan with anti-immunosuppressive activity. 1-methyl-d-tryptophan inhibits the enzyme indoleamine 2,3-dioxygenase (IDO), which degrades the essential amino acid tryptophan, and may increase or maintain tryptophan levels important to T cell function. Tryptophan depletion is associated with immunosuppression involving T cell arrest and anergy. (NCI Thesaurus) 



 
 
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Last updated: Oct 2017
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