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1 result for Name/Synonym equals GILOTRIF 
PropertyValue
Drug Name: Afatinib dimaleate [USAN] View Structure
Description: A radiation sensitizing agent and an ErbB2 tyrosine kinase inhibitor.

NCI: An orally bioavailable dual receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. Afatinib irreversibly binds to and inhibits human epidermal growth factor receptors 1 and 2 (EGFR-1; HER2), which may result in the inhibition of tumor growth and angiogenesis. EGFR/HER2 are RTKs that belong to the EGFR superfamily; both play major roles in tumor cell proliferation and tumor vascularization and are overexpressed in many cancer cell types. (NCI Thesaurus) 
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Last updated: Dec 2022
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