||Inhibits VEGF-R2 and PDGF-Rbeta tyrosine kinase; has antineoplastic activity.
NCI: sunitinib listen (soo-NIH-tih-nib) A drug used to treat certain types of pancreatic cancer. It is also used to treat gastrointestinal stromal tumors (GIST) in some patients and to treat advanced kidney cancer. It is being studied in the treatment of other types of cancer. Sunitinib stops cancer cells from dividing and may prevent the growth of new blood vessels that tumors need to grow. It is a type of tyrosine kinase inhibitor and a type of angiogenesis inhibitor. Also called SU011248, SU11248, sunitinib malate, and Sutent.