CONDITION

STATUS

TRIAL TITLE

INTERVENTIONS

SPONSOR

PHASE

SIZE

FUNDED BY

STUDY TYPE

STUDY DESIGN

NCT ID

OTHER IDS

START DATE

COMPLETION DATE

Partial Epilepsies

Active, not recruiting

To Determine Tolerability and Efficacy of Long-Term Oral Lacosamide in Patients With Partial Seizures

Drug lacosamide

UCB

Phase II

500

INDUSTRY

Interventional

Treatment;

Non-Randomized;�� Open Label; Uncontrolled;��

Single Group Assignment;�� Safety/Efficacy Study

NCT00552305

SP615

Aug-01

Oct-08

Epilepsy

Completed

SPM 927 (400mg/Day and 600mg/Day) as Adjunctive Therapy in Subjects With Partial Seizures With or Without Secondary Generalization

Drug

SPM 927

UCB

Phase III

400

INDUSTRY

Interventional

Treatment;�� Randomized;�� Double-Blind;�� Placebo Control;�� Parallel Assignment;�� Safety/Efficacy Study

NCT00136019

SP754

Mar-04

Aug-06

Partial Seizures With or Without Secondary Generalization

Completed

A Multicenter, Double-Blind, Randomized, Placebo-Controlled, Parallel Group Trial to Investigate the Efficacy and Safety of SPM 927 (200mg/Day and 400mg/Day) as Adjunctive Therapy in Subjects With Partial Seizures With or Without Secondary Generalization

Drug

SPM 927

UCB

Phase III

 

INDUSTRY

Interventional

Treatment;�� Randomized;�� Double-Blind;�� Placebo Control;�� Parallel Assignment

NCT00220415

SP755

May-04

Jan-06

Partial Epilepsies

Active, not recruiting

Determine Safety and Efficacy of Long-Term Oral Lacosamide in Patients With Partial Seizures

Drug lacosamide

UCB

Phase III

308

INDUSTRY

Interventional

Treatment;

Non-Randomized;�� Open Label;�� Uncontrolled;

Single Group Assignment;�� Safety/Efficacy Study

NCT00522275

SP756

Oct-04

Apr-10

Epilepsy

Active, not recruiting

Assess Safety and Efficacy of Lacosamide in Patients With Partial Seizures

Drug Lacosamide

UCB

Phase III

376

INDUSTRY

Interventional

Treatment;�� Open Label;�� Uncontrolled;�� Single Group Assignment;�� Safety/Efficacy Study

NCT00515619

SP774

Dec-04

Oct-08

Epilepsies, Partial

Completed

Safety and Tolerability of Intravenous SPM 927 as Replacement for Oral SPM 927 in Subjects With Partial Seizures

Drug SPM 927

UCB

Phase II / Phase III

160

INDUSTRY

Interventional

Treatment;�� Non-Randomized;�� Open Label;�� Dose Comparison;�� Single Group Assignment

NCT00151879

SP757

Feb-05

May-06

Epilepsy

Recruiting

Trial to Demonstrate the Efficacy and Safety of Conversion to Lacosamide Monotherapy for Partial-Onset Seizures

 

Drug lacosamide;�� Drug lacosamide

UCB

Phase III

357

INDUSTRY

Interventional

Treatment;�� Randomized;�� Double Blind (Subject, Caregiver, Investigator);�� Parallel Assignment;�� Safety/Efficacy Study

NCT00520741

SP902

Aug-07

Oct-09

Epilepsy

Enrolling by invitation

Trial to Assess Long-Term Lacosamide (LCM) Monotherapy Use and Safety of LCM Monotherapy and Adjunctive Therapy for Partial-Onset Seizures

Drug Lacosamide

UCB

Phase III

225

INDUSTRY

Interventional

Treatment;��

Open Label;�� Single Group Assignment;�� Safety/Efficacy Study

NCT00530855

SP904

Jan-08

Dec-10

Partial Epilepsies

Recruiting

Trial to Assess the Safety of a Single Dose of iv Lacosamide Followed by Twice Daily Oral Lacosamide in Patients With Partial-Onset Seizures

Drug Lacosamide

UCB

Phase III

100

 

 

Treatment;

Non-Randomized; Open Label; Single Group Assignment;SafetyStudy

NCT00655551

SP925

Mar-08

Sep-09

Partial������������ Epilepsies

Recruiting

Trial to Assess the Long-Term Safety of Oral Lacosamide in Patients With Partial-Onset Seizures

Drug Lacosamide

UCB

Phase III

100

 

 

Treatment;Non-Randomized;Open Label; Single Group Assignment;Safety Study

NCT00655486

SP926

Apr-08

Apr-10

Fibromyalgia Syndrome

Completed

A Trial to Assess Lacosamide in Subjects With Signs and Symptoms Associated With Fibromyalgia Syndrome

Drug Lacosamide;�� Other placebo

UCB

Phase II

416

INDUSTRY

Interventional

Treatment;�� Randomized;�� Double Blind (Subject, Investigator);�� Placebo Control;�� Parallel Assignment;�� Safety/Efficacy Study

NCT00401830

SP887

Oct-06

Feb-08

Migraine Disorders

Active, not recruiting

A Trial of Lacosamide for Migraine Prophylaxis

Drug Lacosamide;�� Other Placebo;�� Drug Lacosamide

UCB

Phase II

192

INDUSTRY

Interventional

Treatment;�� Randomized;�� Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor);�� Placebo Control;�� Parallel Assignment;�� Safety/Efficacy Study

NCT00440518

 

SP906

Feb-07

Jul-08

Postherpetic Neuralgia

Completed

An Open-Label Follow-on Trial to Assess the Long-Term Safety and Efficacy of Oral SPM 927 in Subjects With Postherpetic Neuralgia (PHN)

Drug SPM 927

UCB

Phase II

 

INDUSTRY

Interventional

Treatment;�� Non-Randomized;�� Open Label;�� Uncontrolled;�� Single Group Assignment

NCT00238511

SP690

Nov-02

Jan-05

Chronic Refractory Neuropathic Pain

Active, not recruiting

A Follow-On Trial to Assess the Long Term Safety and Efficacy of SPM 927 in Painful Distal Diabetic Neuropathy

Drug Lacosamide

UCB

Phase II

7

INDUSTRY

Interventional

Treatment;�� Non-Randomized;�� Open Label;�� Uncontrolled;�� Single Group Assignment;�� Safety/Efficacy Study

NCT00237458

SP647

May-01

Dec-08

Diabetic Neuropathy

Completed

A Trial to Assess the Efficacy and Safety of SPM 927 (Lacosamide) in Subjects With Painful Distal Diabetic Neuropathy

Drug SPM 927

UCB

Phase III

357

INDUSTRY

Interventional

Treatment;�� Randomized;�� Double-Blind;�� Placebo Control;�� Parallel Assignment;�� Safety/Efficacy Study

NCT00238524

SP743

Dec-03

Jan-05

Diabetic Neuropathy

Completed

A Trial to Assess the Efficacy and Safety of SPM 927 in Subjects With Painful Distal Diabetic Neuropathy

Drug SPM 927

UCB

Phase II /Phase III

496

INDUSTRY

Interventional

Treatment;�� Randomized;�� Double-Blind;�� Placebo Control;�� Parallel Assignment

NCT00235469

SP742

Apr-04

Jun-05

Painful Diabetic Neuropathy

Active, not recruiting

Open-Label, Follow-on Trial to Assess the Long-Term Safety and Efficacy of Lacosamide in Subjects With Painful Distal Diabetic Neuropathy.

Drug Lacosamide

UCB

Phase III

614

INDUSTRY

Interventional

Treatment;�� Non-Randomized;�� Open Label;�� Uncontrolled;�� Single Group Assignment;�� Safety Study

NCT00546351

SP746,�� Eudra CT-No.,�� 2004-000551-42

May-04

Dec-08

Diabetic Neuropathy

Active, not recruiting

A Follow-On Trial to Assess the Long Term Safety and Efficacy of SPM 927 in Painful Distal Diabetic Neuropathy

Drug lacosamide

UCB

Phase II /Phase III

452

INDUSTRY

Interventional

Treatment;�� Non-Randomized;�� Open Label;�� Uncontrolled;�� Single Group Assignment;�� Safety/Efficacy Study

NCT00235443

SP745

Sep-04

Sep-08

Diabetic Neuropathies

Completed

Trial to Assess the Efficacy and Safety of SPM 927 (200, 400, and 600mg/Day) in Subjects With Painful Distal Diabetic Neuropathy

Drug SPM 927

UCB

Phase III

654

INDUSTRY

Interventional

Treatment;�� Randomized;�� Double-Blind;�� Placebo Control;�� Parallel Assignment;�� Safety/Efficacy Study

NCT00135109

SP768

Oct-04

Dec-05

Painful Diabetic Neuropathy

Completed

A Trial to Assess the Long-Term Safety and Efficacy of Lacosamide in Subjects With Painful Diabetic Neuropathy

Drug lacosamide

UCB

Phase III

371

INDUSTRY

Interventional

Treatment;�� Non-Randomized;�� Open Label;�� Uncontrolled;�� Single Group Assignment

NCT00220337

SP830

Dec-04

Oct-07

Painful Diabetic Neuropathy

Completed

A Trial to Assess the Efficacy and Safety of 400mg/Day Lacosamide in Subjects With Painful Diabetic Neuropathy

Drug SPM 929

UCB

Phase III

537

INDUSTRY

Interventional

Treatment;�� Randomized;�� Double-Blind;�� Placebo Control;�� Parallel Assignment;�� Safety/Efficacy Study

NCT00350103

SP874

Jun-06

Jun-07