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Category Names, Results, and Descriptions


Narcotic Analgesics (0) see Narcotics

Narcotic Antagonists (39) • Agents inhibiting the effect of narcotics on the central nervous system. MeSH

Narcotic Effect (0) see Narcotics

Narcotics (83) • Agents that induce NARCOSIS. Narcotics include agents that cause somnolence or induced sleep (STUPOR); natural or synthetic derivatives of OPIUM or MORPHINE or any substance that has such effects. They are potent inducers of ANALGESIA and OPIOID-RELATED DISORDERS. MeSH

Nasal Decongestants (12) • Drugs designed to treat inflammation of the nasal passages, generally the result of an infection (more often than not the common cold) or an allergy related condition, e.g., hay fever. The inflammation involves swelling of the mucous membrane that lines the nasal passages and results in inordinate mucus production. The primary class of nasal decongestants are vasoconstrictor agents. (From PharmAssist, The Family Guide to Health and Medicine, 1993) MeSH

Natriuretic Agents (89) • Endogenous or exogenous chemicals that regulate the WATER-ELECTROLYTE BALANCE in the body. They consist of peptides and non-peptide compounds. MeSH

Natriuretic Effect (0) see Natriuretic Agents

Natriuretic Hormones (0) see Natriuretic Agents

Neurohormones (0) see Neurotransmitter Agents

Neurohumors (0) see Neurotransmitter Agents

Neurokinin-1 Receptor Antagonists (23) • Compounds that inhibit or block the activity of NEUROKININ-1 RECEPTORS. MeSH

Neuromodulators (0) see Neurotransmitter Agents

Neuromuscular Agents (64) • Drugs used for their actions on skeletal muscle. Included are agents that act directly on skeletal muscle, those that alter neuromuscular transmission (NEUROMUSCULAR BLOCKING AGENTS), and drugs that act centrally as skeletal muscle relaxants (MUSCLE RELAXANTS, CENTRAL). Drugs used in the treatment of movement disorders are ANTI-DYSKINESIA AGENTS. MeSH

Neuromuscular Blocking Agents (30) • Drugs that interrupt transmission of nerve impulses at the skeletal neuromuscular junction. They can be of two types, competitive, stabilizing blockers (NEUROMUSCULAR NONDEPOLARIZING AGENTS) or noncompetitive, depolarizing agents (NEUROMUSCULAR DEPOLARIZING AGENTS). Both prevent acetylcholine from triggering the muscle contraction and they are used as anesthesia adjuvants, as relaxants during electroshock, in convulsive states, etc. MeSH

Neuromuscular Depolarizing Agents (9) • Drugs that interrupt transmission at the skeletal neuromuscular junction by causing sustained depolarization of the motor end plate. These agents are primarily used as adjuvants in surgical anesthesia to cause skeletal muscle relaxation. MeSH

Neuromuscular Effect (0) see Neuromuscular Agents

Neuromuscular Nondepolarizing Agents (19) • Drugs that interrupt transmission at the skeletal neuromuscular junction without causing depolarization of the motor end plate. They prevent acetylcholine from triggering muscle contraction and are used as muscle relaxants during electroshock treatments, in convulsive states, and as anesthesia adjuvants. MeSH

Neuroprotective Agents (74) • Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids. MeSH

Neuroprotective Effect (0) see Neuroprotective Agents

Neuroregulators (0) see Neurotransmitter Agents

Neurosteroids (8) see Neurotransmitter Agents

Neurotoxins (23) • Toxic substances from microorganisms, plants or animals that interfere with the functions of the nervous system. Most venoms contain neurotoxic substances. Myotoxins are included in this concept. MeSH

Neurotransmitter Agents (1217) • Substances used for their pharmacological actions on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function. MeSH

Neurotransmitter Agentssss (1)

Neurotransmitter Uptake Inhibitors (82) • Drugs that inhibit the transport of neurotransmitters into axon terminals or into storage vesicles within terminals. For many transmitters, uptake determines the time course of transmitter action so inhibiting uptake prolongs the activity of the transmitter. Blocking uptake may also deplete available transmitter stores. Many clinically important drugs are uptake inhibitors although the indirect reactions of the brain rather than the acute block of uptake itself is often responsible for the therapeutic effects. MeSH

Neurotransmitters (0) see Neurotransmitter Agents

Neutrophil-Derived Relaxant Factor (0) see Endothelium-Dependent Relaxing Factors

Nicotinic Agents (0) see Cholinergic Agents

Nicotinic Agonists (8) • Drugs that bind to and activate nicotinic cholinergic receptors (RECEPTORS, NICOTINIC). Nicotinic agonists act at postganglionic nicotinic receptors, at neuroeffector junctions in the peripheral nervous system, and at nicotinic receptors in the central nervous system. Agents that function as neuromuscular depolarizing blocking agents are included here because they activate nicotinic receptors, although they are used clinically to block nicotinic transmission. MeSH

Nicotinic Antagonists (27) • Drugs that bind to nicotinic cholinergic receptors (RECEPTORS, NICOTINIC) and block the actions of acetylcholine or cholinergic agonists. Nicotinic antagonists block synaptic transmission at autonomic ganglia, the skeletal neuromuscular junction, and at central nervous system nicotinic synapses. MeSH

Nicotinic Effect (0) see Cholinergic Agents

Nitric Oxide Donors (20) • A diverse group of agents, with unique chemical structures and biochemical requirements, which generate NITRIC OXIDE. These compounds have been used in the treatment of cardiovascular diseases and the management of acute myocardial infarction, acute and chronic congestive heart failure, and surgical control of blood pressure. (Adv Pharmacol 1995;34:361-81) MeSH

Nootropic Agents (31) • Drugs used to specifically facilitate learning or memory, particularly to prevent the cognitive deficits associated with dementias. These drugs act by a variety of mechanisms. While no potent nootropic drugs have yet been accepted for general use, several are being actively investigated. MeSH

Noxae (512) • Agents capable of exerting a harmful effect on the body. MeSH

Nucleic Acid Probes (2)

Nucleic Acid Synthesis Inhibitors (99) • Compounds that inhibit cell production of DNA or RNA. MeSH

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Last updated: Sep 2022