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Category Names, Results, and Descriptions

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Schistosomicides (15) • Agents that act systemically to kill adult schistosomes. MeSH

Schizonticides (0) see Antiprotozoal Agents

Sclerosing Agents (0) see Sclerosing Solutions

Sclerosing Drugs (0) see Sclerosing Solutions

Sclerosing Injections (0) see Sclerosing Solutions

Sclerosing Solutions (7) • Chemical agents injected into blood vessels and lymphatic sinuses to shrink or cause localized THROMBOSIS; FIBROSIS, and obliteration of the vessels. This treatment is applied in a number of conditions such as VARICOSE VEINS; HEMORRHOIDS; GASTRIC VARICES; ESOPHAGEAL VARICES; PEPTIC ULCER HEMORRHAGE. MeSH

Sedative Effect (0) see Hypnotics and Sedatives

Sedatives (0) see Hypnotics and Sedatives

Selective Angiotensin II Receptor Antagonists (0) see Angiotensin II Type 1 Receptor Blockers

Selective Estrogen Receptor Modulators (12) • A structurally diverse group of compounds distinguished from ESTROGENS by their ability to bind and activate ESTROGEN RECEPTORS but act as either an agonist or antagonist depending on the tissue type and hormonal milieu. They are classified as either first generation because they demonstrate estrogen agonist properties in the ENDOMETRIUM or second generation based on their patterns of tissue specificity. (Horm Res 1997;48:155-63) MeSH

Selective non-prostanoid IP prostacyclin receptor agonist. (1)

Selective Serotonin Reuptake Inhibitors (0) see Serotonin Uptake Inhibitors

Sensory System Agents (476) • Drugs that act on neuronal sensory receptors resulting in an increase, decrease, or modification of afferent nerve activity. (From Smith and Reynard, Textbook of Pharmacology, 1991, p367) MeSH

Sequestering Agents (91) • Compounds that bind to and reduce the biological availability of a chemical or pharmaceutical agent. MeSH

Serine Proteinase Inhibitors (56) • Exogenous or endogenous compounds which inhibit SERINE ENDOPEPTIDASES. MeSH

Serine Proteinase Inhibitors, Endogenous (0) see Serine Proteinase Inhibitors

Serine Proteinase Inhibitors, Exogenous (0) see Serine Proteinase Inhibitors

Serotonin 5-HT1 Receptor Agonists (11) • Endogenous compounds and drugs that specifically stimulate SEROTONIN 5-HT1 RECEPTORS. Included under this heading are agonists for one or more of the specific 5-HT1 receptor subtypes. MeSH

Serotonin 5-HT1 Receptor Antagonists (4) • Drugs that bind to but do not activate SEROTONIN 5-HT1 RECEPTORS, thereby blocking the actions of SEROTONIN 5-HT1 RECEPTOR AGONISTS. Included under this heading are antagonists for one or more of the specific 5-HT1 receptor subtypes. MeSH

Serotonin 5-HT1A Receptor Agonists (0) see Serotonin 5-HT1 Receptor Agonists

Serotonin 5-HT1A Receptor Antagonists (0) see Serotonin 5-HT1 Receptor Antagonists

Serotonin 5-HT1B Receptor Agonists (0) see Serotonin 5-HT1 Receptor Agonists

Serotonin 5-HT1B Receptor Antagonists (0) see Serotonin 5-HT1 Receptor Antagonists

Serotonin 5-HT1B-D Agonists (0) see Serotonin 5-HT1 Receptor Agonists

Serotonin 5-HT1B-D Antagonists (0) see Serotonin 5-HT1 Receptor Antagonists

Serotonin 5-HT1D Receptor Agonists (0) see Serotonin 5-HT1 Receptor Agonists

Serotonin 5-HT1D Receptor Antagonists (0) see Serotonin 5-HT1 Receptor Antagonists

Serotonin 5-HT2 Receptor Agonists (3)

Serotonin 5-HT2 Receptor Antagonists (3) • Drugs that bind to but do not activate SEROTONIN 5-HT2 RECEPTORS, thereby blocking the actions of SEROTONIN or SEROTONIN 5-HT2 RECEPTOR AGONISTS. Included under this heading are antagonists for one or more specific 5-HT2 receptor subtypes. MeSH

Serotonin 5-HT2A Receptor Antagonists (0) see Serotonin 5-HT2 Receptor Antagonists

Serotonin 5-HT2B Receptor Antagonists (0) see Serotonin 5-HT2 Receptor Antagonists

Serotonin 5-HT2C Receptor Antagonists (0) see Serotonin 5-HT2 Receptor Antagonists

Serotonin 5-HT3 Receptor Antagonists (2)

Serotonin 5-HT4 Receptor Agonists (2)

Serotonin Agents (165) • Drugs used for their effects on serotonergic systems. Among these are drugs that affect serotonin receptors, the life cycle of serotonin, and the survival of serotonergic neurons. MeSH

Serotonin Agonists (12)

Serotonin and Noradrenaline Reuptake Inhibitors (3) • Drugs that selectively block or suppress the plasma membrane transport of SEROTONIN and NORADRENALINE into axon terminals and are used as ANTIDEPRESSIVE AGENTS. MeSH

Serotonin Antagonists (81) • Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or SEROTONIN RECEPTOR AGONISTS. MeSH

Serotonin Effect (0) see Serotonin Agents

Serotonin Receptor Agonists (65) • Endogenous compounds and drugs that bind to and activate SEROTONIN RECEPTORS. Many serotonin receptor agonists are used as ANTIDEPRESSANTS; ANXIOLYTICS; and in the treatment of MIGRAINE DISORDERS. MeSH

Serotonin Uptake Inhibitors (22) • Compounds that specifically inhibit the reuptake of serotonin in the brain. MeSH

Sex Hormone Synthesis Inhibitors (0) see Steroid Synthesis Inhibitors

Siderophores (10) • Low-molecular-weight compounds produced by microorganisms that aid in the transport and sequestration of ferric iron. (The Encyclopedia of Molecular Biology, 1994) MeSH

Skeletal Muscle Relaxants (0) see Neuromuscular Agents

Sleep Aids, Pharmaceutical (2) • Drugs used to induce SLEEP, prevent SLEEPLESSNESS, or treat SLEEP INITIATION AND MAINTENANCE DISORDERS. MeSH

Small GTPase Activators (0) see GTP Phosphohydrolase Activators

Sodium Channel Agonists (1)

Sodium Channel Blockers (25) • A class of drugs that act by inhibition of sodium influx through cell membranes. Blockade of sodium channels slows the rate and amplitude of initial rapid depolarization, reduces cell excitability, and reduces conduction velocity. MeSH

Sodium Chloride Symporter Inhibitors (14) • Agents that inhibit SODIUM CHLORIDE SYMPORTERS. They act as DIURETICS. Excess use is associated with HYPOKALEMIA. MeSH

Sodium Ionophores (1) • Chemical agents that increase the permeability of CELL MEMBRANES to SODIUM ions. MeSH

Sodium Potassium Chloride Symporter Inhibitors (5) • Agents that inhibit SODIUM-POTASSIUM-CHLORIDE SYMPORTERS which are concentrated in the thick ascending limb at the junction of the LOOP OF HENLE and KIDNEY TUBULES, DISTAL. They act as DIURETICS. Excess use is associated with HYPOKALEMIA and HYPERGLYCEMIA. MeSH

Soil Pollutants (4) • Substances which pollute the soil. Use for soil pollutants in general or for which there is no specific heading. MeSH

Solvents (21) • Liquids that dissolve other substances (solutes), generally solids, without any change in chemical composition, as, water containing sugar. (Grant & Hackh's Chemical Dictionary, 5th ed) MeSH

Spermatocidal Agents (5) • Chemical substances that are destructive to spermatozoa used as topically administered vaginal contraceptives. MeSH

Stabilizing Agents (0) see Excipients

Stains (0) see Coloring Agents

Steroid Synthesis Inhibitors (1) • Compounds that bind to and inhibit enzymes involved in the synthesis of STEROIDS. MeSH

Stromelysin Inhibitors (0) see Matrix Metalloproteinase Inhibitors

Sugar Substitutes (0) see Sweetening Agents

Sulfhydryl Compound Antagonists (0) see Sulfhydryl Reagents

Sulfhydryl Compounds Inhibitors (0) see Sulfhydryl Reagents

Sulfhydryl Reagents (10) • Chemical agents that react with SH groups. This is a chemically diverse group that is used for a variety of purposes. Among these are enzyme inhibition, enzyme reactivation or protection, and labelling. MeSH

Sunscreening Agents (10) • Chemical or physical agents that protect the skin from sunburn and erythema by absorbing or blocking ultraviolet radiation. MeSH

Surface-Active Agents (65) • Agents that modify interfacial tension of water; usually substances that have one lipophilic and one hydrophilic group in the molecule; includes soaps, detergents, emulsifiers, dispersing and wetting agents, and several groups of antiseptics. MeSH

Surfactants (0) see Surface-Active Agents

Surgical Fixation Devices (9)

Suspending Agents (0) see Excipients

Sustained-Release Preparations (0) see Delayed-Action Preparations

Sweetening Agents (19) • Substances that sweeten food, beverages, medications, etc., such as sugar, saccharine or other low-calorie synthetic products. (From Random House Unabridged Dictionary, 2d ed) MeSH

Sympathetic Transmitter Releasers (0) see Adrenergic Agents

Sympatholytic Effect (0) see Sympatholytics

Sympatholytics (24) • Drugs that inhibit the actions of the sympathetic nervous system by any mechanism. The most common of these are the ADRENERGIC ANTAGONISTS and drugs that deplete norepinephrine or reduce the release of transmitters from adrenergic postganglionic terminals (see ADRENERGIC AGENTS). Drugs that act in the central nervous system to reduce sympathetic activity (e.g., centrally acting alpha-2 adrenergic agonists, see ADRENERGIC ALPHA-AGONISTS) are included here. MeSH

Sympathomimetic Effect (0) see Sympathomimetics

Sympathomimetics (61) • Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. MeSH

Synthetic Detergent (0) see Detergents

 
 
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