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Category Names, Results, and Descriptions

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Immunologic Factors (283) • Biologically active substances whose activities affect or play a role in the functioning of the immune system. MeSH

Immunomodulators (0) see Immunologic Factors

Immunosuppressive Agents (116) • Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging. MeSH

Immunotoxins (2)

Incretin Effect (0) see Incretins

Incretins (11) • Peptides which stimulate INSULIN release from the PANCREATIC BETA CELLS following oral nutrient ingestion, or postprandially. MeSH

Indicators (0) see Indicators and Reagents

Indicators and Reagents (453) • Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499) MeSH

Indirect Thrombin Inhibitors (0) see Anticoagulants

Inflammatory Agents, Non-Steroidal (1)

Insect Repellents (8) • Substances causing insects to turn away from them or reject them as food. MeSH

Insecticides (127) • Pesticides designed to control insects that are harmful to man. The insects may be directly harmful, as those acting as disease vectors, or indirectly harmful, as destroyers of crops, food products, or textile fabrics. MeSH

Insecticides, Organothiophosphate, Antagonists (0) see Cholinesterase Reactivators

Insulin Antagonists (1) • Compounds which inhibit or antagonize the biosynthesis or action of insulin. MeSH

Intercalating Agents (21) • Agents that are capable of inserting themselves between the successive bases in DNA, thus kinking, uncoiling or otherwise deforming it and therefore preventing its proper functioning. They are used in the study of DNA. MeSH

Interferon Inducers (16) • Agents that promote the production and release of interferons. They include mitogens, lipopolysaccharides, and the synthetic polymers Poly A-U and Poly I-C. Viruses, bacteria, and protozoa have been also known to induce interferons. MeSH

Intestinal alpha-Amylase Inhibitors (0) see Glycoside Hydrolase Inhibitors

Intravenous Feeding Solutions (0) see Parenteral Nutrition Solutions

Ion Exchange Resins (4)

Ionophores (11) • Chemical agents that increase the permeability of biological or artificial lipid membranes to specific ions. Most ionophores are relatively small organic molecules that act as mobile carriers within membranes or coalesce to form ion permeable channels across membranes. Many are antibiotics, and many act as uncoupling agents by short-circuiting the proton gradient across mitochondrial membranes. MeSH

Iron Chelating Agents (29) • Organic chemicals that form two or more coordination links with an iron ion. Once coordination has occurred, the complex formed is called a chelate. The iron-binding porphyrin group of hemoglobin is an example of a metal chelate found in biological systems. MeSH

Irritants (11) • Drugs that act locally on cutaneous or mucosal surfaces to produce inflammation; those that cause redness due to hyperemia are rubefacients; those that raise blisters are vesicants and those that penetrate sebaceous glands and cause abscesses are pustulants; tear gases and mustard gases are also irritants. MeSH

Isohemagglutinins (0) see Hemagglutinins

 
 
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